REdo transcatheter aortic VALVE implantation for the management of transcatheter aortic valve failure: Design and rationale of the REVALVE study

Background: The expansion of transcatheter aortic valve implantation (TAVI) into younger and lower risk patients increases the likelihood of future reintervention on the valve due to bioprosthetic valve failure (BVF). However, little is known about the feasibility and outcomes of redo TAVI for BVF. Methods: REVALVE is an investigator-initiated, open-label, prospective registry, enrolling 300 patients undergoing redo TAVI in approximately 75 centres in 11 countries in Europe and the Middle Eas...

Impact of CHA2DS2‐VASc Score in the Outcomes of Patients Undergoing a Simplified Pathway for Percutaneous Left Atrial Appendage Closure

Background: Percutaneous left atrial appendage closure (LAAC) is usually performed after a pre-procedural evaluation by transesophageal echocardiography (TOE) or cardiac computed tomography angiography (CCTA). Nevertheless, these ad-hoc examinations imply an additional use of hospital resources and time spending. Aims: To investigate long-term clinical outcomes, effectiveness and safety of performing LAAC procedures without pre-procedural imaging assessment in patients with high and very high...

Comparison between severe R-L and R-NC raphe-type bicuspid aortic valve stenosis treated with TAVI: insights from the international AD HOC Registry

Background: Sievers type 1 bicuspid aortic valve (BAV) stenosis presents unique challenges for trans-catheter aortic valve implantation (TAVI), particularly when calcified raphe is present. The impact of raphe localization on TAVI outcomes remains unclear. Objectives: This study aimed to compare procedural and clinical outcomes in patients with right-left (R-L) and right-non coronary (R-NC) raphe-type BAV treated with TAVI. Methods: Between January 2016 and October 2023, 956 consecutive patie...

TAVR for Asymptomatic Severe Aortic Stenosis