Neutrophil/lymphocyte ratio: a potential biomarker in patients with head and neck squamous cell carcinoma treated with immune checkpoint inhibitors

Introduction: Literature has shown that there is a correlation between increased circulatory inflammatory factors and negative prognosis, which can be evaluated through the using the neutrophil and lymphocyte ratio (NLR). The aim of this research is to investigate the predictive and prognostic role of the NLR in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) patients, treated with immunotherapy, and its correlation to the overall survival (OS), progression free surviva...

Editorial: The digital transformation of dental and maxillofacial practice towards preventive, personalised, and precision medicine

Efficient clustering for NOMA with THz mMIMO D2D inspired 6G system model

Terahertz (THz) communication, offering unprecedented bandwidth, is a key enabler for the high data rates envisioned in 6G wireless networks. To further enhance capacity and spectral efficiency, this paper proposes a novel 6G hybrid system model integrating THz communication with massive multiple-input multiple-output (mMIMO), cooperative non-orthogonal multi-ple access (NOMA), and device-to-device (D2D) communication within a heterogeneous network architecture comprising macrocells and small...

Text-guided diverse-expression diffusion model for molecule generation

The task of molecule generation guided by specific text descriptions has been proposed to generate molecules that match given text inputs. Mainstream methods typically use simplified molecular input line entry system (SMILES) to represent molecules and rely on diffusion models or autoregressive structures for modeling. However, the one-to-many mapping diversity when using SMILES to represent molecules causes existing methods to require complex model architectures and larger training datasets ...