Background: Autonomic diabetic neuropathy is a challenging chronic complication of long-standing diabetes manifested with hypotension, syncope, gastroparesis, diarrhoea, constipation, bladder dysfunction, sexual dysfunction, cardiac arrest and/or sudden death. Objective: We present a case of diabetic gastroparesis in an old woman. Methods and Results: An 83 year-old woman with 40-year history of type 2 diabetes was admitted with hypoglycaemia, malnutrition, persistent vomiting and obstinate constipation. After several unsuccessful attempts with different therapies, we administered intravenous azythromycin (500 mg/day). After three days of treatment, vomiting was resolved and the patient evacuated normal faeces with notable improvement in the general conditions and metabolic control. Conclusions: The macrolide antibiotic azithromycin, with strong prokinetic properties, is a therapeutical option in the treatment of diabetic gastroparesis.
"Azithromycin" in an old woman with diabetic gastroparesis [L’AZITROMICINA NEL TRATTAMENTO DELLA GASTROPARESI DIABETICA NELL’ANZIANO: UN CASO CLINICO]
DOMINGUEZ L.J.;
2008-01-01
Abstract
Background: Autonomic diabetic neuropathy is a challenging chronic complication of long-standing diabetes manifested with hypotension, syncope, gastroparesis, diarrhoea, constipation, bladder dysfunction, sexual dysfunction, cardiac arrest and/or sudden death. Objective: We present a case of diabetic gastroparesis in an old woman. Methods and Results: An 83 year-old woman with 40-year history of type 2 diabetes was admitted with hypoglycaemia, malnutrition, persistent vomiting and obstinate constipation. After several unsuccessful attempts with different therapies, we administered intravenous azythromycin (500 mg/day). After three days of treatment, vomiting was resolved and the patient evacuated normal faeces with notable improvement in the general conditions and metabolic control. Conclusions: The macrolide antibiotic azithromycin, with strong prokinetic properties, is a therapeutical option in the treatment of diabetic gastroparesis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
