Phosphodiesterase 2A, a cAMP-hydrolysing enzyme, is essential for mouse development, however the cause of Pde2A knockout embryonic lethality is unknown. To understand if Pde2A plays a role in cardiac development, hearts of Pde2A deficient embryos were analysed at different stage of development.

Critical role of phosphodiesterase 2A in mouse congenital heart defects

Assenza Maria Rita;Barbagallo Federica;
2018-01-01

Abstract

Phosphodiesterase 2A, a cAMP-hydrolysing enzyme, is essential for mouse development, however the cause of Pde2A knockout embryonic lethality is unknown. To understand if Pde2A plays a role in cardiac development, hearts of Pde2A deficient embryos were analysed at different stage of development.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11387/154127
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