Objective: To prospectively assess the nutritional status of patients undergoing surgery for esophageal cancer, as well as to assess the prognostic value of body mass index, preoperative weight loss and albumin levels in determining the surgical outcome and overall survival. Patients and methods: Seventy-two patients undergoing curative esophageal resection for cancer were recruited from November 2004 to April 2010. Weight loss was recorded in all patients. Serum total protein, albumin and body mass index were measured at the first visit in the preoperative assessment. Surgical outcomes and mortality were recorded. The chi-square test and Fisher's exact test were used to compare noncontinuous and continuous data, as appropriate. Survival curves were determined using the Kaplan-Meier method. Results: Fifty-four patients underwent subtotal esophagectomy and 18 patients total esophagectomy. Mean body mass index at initial assessment was 24.2. Seven patients had a body mass index of 18.5 or less. Thirty-four patients had ideal body weight and 31 patients had a body mass index of more than 25. There were 4 postoperative deaths, 35 patients experienced major postoperative complications, and 33 patients had an uneventful postoperative course. There was no statistical difference in mean body mass index, serum albumin or weight loss between patients with and without complications. Similarly, no correlation was found between body mass index, serum albumin, weight loss and overall survival. Conclusions: Body mass index proved quite well preserved in this cohort of patients with operable esophageal cancer. In our series no association between body mass index, serum albumin or weight loss and postoperative complications or survival was detected. © 2012 SINPE-GASAPE.
Impact on surgical outcome of body mass index, serum albumin levels and weight loss in a prospectively assessed cohort of patients undergoing curative resection for esophageal cancer
Luca F.;
2012-01-01
Abstract
Objective: To prospectively assess the nutritional status of patients undergoing surgery for esophageal cancer, as well as to assess the prognostic value of body mass index, preoperative weight loss and albumin levels in determining the surgical outcome and overall survival. Patients and methods: Seventy-two patients undergoing curative esophageal resection for cancer were recruited from November 2004 to April 2010. Weight loss was recorded in all patients. Serum total protein, albumin and body mass index were measured at the first visit in the preoperative assessment. Surgical outcomes and mortality were recorded. The chi-square test and Fisher's exact test were used to compare noncontinuous and continuous data, as appropriate. Survival curves were determined using the Kaplan-Meier method. Results: Fifty-four patients underwent subtotal esophagectomy and 18 patients total esophagectomy. Mean body mass index at initial assessment was 24.2. Seven patients had a body mass index of 18.5 or less. Thirty-four patients had ideal body weight and 31 patients had a body mass index of more than 25. There were 4 postoperative deaths, 35 patients experienced major postoperative complications, and 33 patients had an uneventful postoperative course. There was no statistical difference in mean body mass index, serum albumin or weight loss between patients with and without complications. Similarly, no correlation was found between body mass index, serum albumin, weight loss and overall survival. Conclusions: Body mass index proved quite well preserved in this cohort of patients with operable esophageal cancer. In our series no association between body mass index, serum albumin or weight loss and postoperative complications or survival was detected. © 2012 SINPE-GASAPE.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
