P-162 Is Resection the Only Choice for the Treatment of Bilobar Colorectal Cancer Metastases?

Introduction: Traditionally multiple bilobar colorectal liver metastases (CRLM) were not considered suitable for radical resection. Only 25% of patients presenting with CRLM are amenable to surgery. We sought to determine the efficacy of combined resection and ablation for CRLM. Methods: Between January 1994 and June 2014, 360 patients underwent surgery for CRLM, were queried from an international multi-institutional database. There were 280 cases who underwent hepatic resection only (Group 1) and 80 hepatic resection and ablation (Group 2). Results: The median number of resected lesions were 3; the median number of ablated lesions were 2. Postoperative complications were similar in the two groups and mortality was nil. Five years overall survival was 48,6% and 80% for Group 1 vs Group 2 respectively (p= 0193). For patients undergoing R0 surgery disease-free survival was 34% vs 50% at 3 years (p= 0,96). Conclusion: Combined resection and ablation is associated with long-term survival in a subset of patients, and represents a potentially curative treatment option for patients with multiple bilobar hepatic metastatic tumours.