The purpose of this study is to review the existing literature on the treatment of endometrial carcinoma with brain metastases. Brain metastases from endometrial cancer are rare and pose significant challenges in treatment, as no standardized approach exists. This study investigates the impact of different therapeutic strategies, including surgery, radiotherapy, systemic therapies, and their combinations, on patient survival. By evaluating these treatments in specific patient subgroups, such as those with solitary brain metastases or multiple brain metastases with extracranial disease, we aim to identify the most effective approaches to improve outcomes. Our findings may provide valuable insights to guide future research and inform clinical decision making for this challenging condition.
Brain Metastasis in Endometrial Cancer: A Systematic Review
Sambataro, Daniela;Gebbia, Vittorio;Di Mattia, Paolo;Lavalle, Salvatore;Pecorino, Basilio;Scandurra, Giuseppa;Scibilia, Giuseppe;
2025-01-01
Abstract
The purpose of this study is to review the existing literature on the treatment of endometrial carcinoma with brain metastases. Brain metastases from endometrial cancer are rare and pose significant challenges in treatment, as no standardized approach exists. This study investigates the impact of different therapeutic strategies, including surgery, radiotherapy, systemic therapies, and their combinations, on patient survival. By evaluating these treatments in specific patient subgroups, such as those with solitary brain metastases or multiple brain metastases with extracranial disease, we aim to identify the most effective approaches to improve outcomes. Our findings may provide valuable insights to guide future research and inform clinical decision making for this challenging condition.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
