IRIS
MALAGUARNERA, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 2.902
EU - Europa 1.932
AS - Asia 898
SA - Sud America 188
AF - Africa 40
Continente sconosciuto - Info sul continente non disponibili 16
OC - Oceania 5
Totale 5.981
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Nazione #
US - Stati Uniti d'America 2.781
IE - Irlanda 452
HK - Hong Kong 400
SG - Singapore 360
GB - Regno Unito 329
UA - Ucraina 303
DE - Germania 219
IT - Italia 175
BR - Brasile 172
SE - Svezia 135
CH - Svizzera 118
CA - Canada 109
FI - Finlandia 92
IN - India 36
HR - Croazia 30
CN - Cina 28
EG - Egitto 24
TR - Turchia 19
FR - Francia 18
CZ - Repubblica Ceca 17
EU - Europa 16
IR - Iran 16
RU - Federazione Russa 14
MX - Messico 9
PH - Filippine 7
AR - Argentina 6
BE - Belgio 6
NL - Olanda 6
TW - Taiwan 6
AU - Australia 4
BD - Bangladesh 4
LT - Lituania 4
MA - Marocco 4
ZA - Sudafrica 4
AE - Emirati Arabi Uniti 3
AT - Austria 3
IL - Israele 3
PE - Perù 3
PK - Pakistan 3
TN - Tunisia 3
CL - Cile 2
EC - Ecuador 2
HU - Ungheria 2
IQ - Iraq 2
KG - Kirghizistan 2
LV - Lettonia 2
NP - Nepal 2
RO - Romania 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BG - Bulgaria 1
CI - Costa d'Avorio 1
CO - Colombia 1
CR - Costa Rica 1
ES - Italia 1
GR - Grecia 1
IS - Islanda 1
JM - Giamaica 1
JP - Giappone 1
KE - Kenya 1
MC - Monaco 1
ML - Mali 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PA - Panama 1
PS - Palestinian Territory 1
SA - Arabia Saudita 1
SC - Seychelles 1
TJ - Tagikistan 1
UY - Uruguay 1
VE - Venezuela 1
VN - Vietnam 1
Totale 5.981
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Città #
Chandler 632
Dublin 438
Hong Kong 396
London 305
Jacksonville 290
Boardman 285
The Dalles 148
Santa Clara 134
Zurich 118
Wilmington 115
Princeton 110
Toronto 102
Singapore 100
Helsinki 92
Ashburn 91
Chicago 66
Bareggio 42
Catania 37
Redmond 32
Zagreb 30
Cairo 18
Brno 17
Milan 15
Munich 14
São Paulo 13
Frankfurt am Main 12
Kocaeli 12
Palermo 11
Norwalk 10
Tappahannock 10
Cambridge 9
Falkenstein 9
Leawood 9
Capo D'orlando 7
Council Bluffs 7
Carrara 6
Des Moines 6
Düsseldorf 6
Fairfield 6
Monmouth Junction 6
New York 6
Taichung 6
Bremen 5
Brussels 5
Gustavo Adolfo Madero 5
Isfahan 5
Rio de Janeiro 5
St Petersburg 5
Strasbourg 5
Andover 4
Bangalore 4
Belo Horizonte 4
Bengaluru 4
Enna 4
Istanbul 4
Manaus 4
Mascalucia 4
New Delhi 4
Piscataway 4
Pune 4
Quezon City 4
Redwood City 4
Ribeirão Preto 4
Rome 4
San Mateo 4
Sorocaba 4
Southend 4
Agrigento 3
Anápolis 3
Aracaju 3
Augusta 3
Bari 3
Campinas 3
Diadema 3
Edinburgh 3
Fortaleza 3
Gevelsberg 3
Guangzhou 3
Lauterbourg 3
Ma On Shan 3
Menlo Park 3
Nanjing 3
Seattle 3
Trieste 3
Woodbridge 3
Zhengzhou 3
Aci Catena 2
Amsterdam 2
Ann Arbor 2
Araraquara 2
Ardabil 2
Bishkek 2
Brasília 2
Brisbane 2
Centuripe 2
Clifton 2
Curitiba 2
Dallas 2
Damietta 2
Dhaka 2
Totale 3.970
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Nome #
Orobanche crenata extracts exerts antitumor activity “in vitro” 148
c-ABL tyrosine kinase inhibits insulin induced proliferation and migration in HepG2 cancer cells: role of focal adhesion kinase 124
p73 tumor suppressor activity is impaired in thyroid cancer 115
p53 family proteins in thyroid cancer 106
TAp63 antagonizes p53 oncosuppressor function in thyroid cancer cells 101
The p53-homologue p63 may promote thyroid cancer progression 97
Immunopurification and quantitative proteomics reveal novel molecular mechanisms of signal diversification between the two insulin receptor isoforms. 93
TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation 92
TAp73? Increases p53 tumor suppressor activity in thyroid cancer cells via inhibition of Mdm2-mediated degradation 87
The Emerging Role of Insulin Receptor Isoforms in Thyroid Cancer: Clinical Implications and New Perspectives 76
Orobanche crenata Forssk. Extract Affects Human Breast Cancer Cell MCF-7 Survival and Viral Replication 75
The IGF2/IRA loop affects the metabolic flexibility of breast cancer cells 74
Targeting Discoidin Domain Receptor 1 as a novel strategy to downregulate Insulin/IGF axis in cancer cells. 72
Discoidin Domain Receptor 1 (DDR1) modulates the expression of insulin receptor and its differential splicing both in thyroid and breast cancer cells 72
Carcinoma anaplastico della tiroide: p53 e p73 hanno un effetto sinergico nell'indurre apoptosi 71
The Insulin/IGF signaling affects the metabolic flexibility of breast cancer cells 71
In poorly differentiated thyroid cancer cells autocrine IR-A/IGF2 signaling activates a feed-forward loop involving DDR1 and its newly identified non-canonical actions. 69
DDR1 è un nuovo regolatore dell’espressione e della funzione del recettore insulinico 66
Chronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (a-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cells. 63
PPAR-γ Agonists As Antineoplastic Agents in Cancers with Dysregulated IGF Axis 62
The insulin receptor isoform A plays a role in thyrospheres growth and differentiation 62
NORMAL AND CANCER THYROID PROGENITOR CELLS: ROLE OF INSULIN RECEPTOR ISOFORMS AND INSULIN-LIKE GROWTH FACTOR RECEPTOR IN GROWTH AND DIFFERENTIATION 61
Discoidin Domain Receptor 1 crosstalk with isoform A of Insulin Receptor affects stem-like phenotype in cancer cells. 61
Proinsulin is a ligand of isoform A of the insulin receptor 60
Discoidin Domain Receptor 1 (DDR1) interacts with IGFI-R and modulates its oncogenic role 60
Comparative proteomic analysis of insulin receptor isoform A and B signaling 58
Co-targeting IR/IGF-1R and DDR1 exerts additive effects in reducing stem-like features in thyrospheres from poorly differentiated thyroid cancer cell lines 57
Thyroid Cancer and Circadian Clock Disruption 56
Role of c-ABL in directing metabolic versus mitogenic effects in insulin receptor signaling 55
Both the insulin receptor isoform A and the IGF-I receptor mediate the effects of IGF-II in human thyroid stem cells 55
Direct Effects of D-Chiro-Inositol on Insulin Signaling and Glucagon Secretion of Pancreatic Alpha Cells 55
Involvement of c-ABL tyrosine kinase in insulin and IGF-I signaling 54
The insulin and igf-I pathway in endocrine glands carcinogenesis 54
Discoidin Domain Receptor 1 affects Insulin Receptor expression and biological actions in breast cancer cells. 53
DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop. 53
A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer 53
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice 53
BRAFV600E mutation is associated with preferential sensitivity to MEK inhibition in thyroid cancer cell lines 53
A novel functional cross-talk between the IGF-I receptor and Discoidin Domain Receptor 1 in breast cancer cells. 53
Candidate genes of SARS-CoV-2 gender susceptibility 53
Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD 53
The crosstalk between the insulin receptor isoform A and Discoidin Domain Receptor 1 regulates breast cancer cell biology and stemness. 52
Cooperation of p73 and p53 in anaplastic thyroid cancer cell apoptosis 52
Recent advances on the stimulatory effects of metals in breast cancer 52
IGF-I and Insulin Receptor families in Cancer 52
Ruolo di p73 nella progressione tumorale tiroidea 51
The combined pharmacological inhibition of Discoidin Domanin Receptor 1 and Insulin Receptor exert antitumor effects in poorly differentiated thyroid cancer cells 51
HMGA1 inhibits the function of p53 family members in thyroid cancer cells 51
Discoidin Domain Receptor 1 modulates Insulin Receptor isoform A expression and biological functions in breast cancer 50
Overlaps between the Insulin and IGF-I receptor in cancer 50
mTOR signling is required for DNA synthesis induced by either RET/PTC, oncogenic RAS or BRAF in rat thyroid PCCL3 cells 50
Modeling BRAF-induced thyroid tumorigenesis in mice:evidence for a causal role of oncogenic BRAF activation on loss of thyroid differentiated function in vivo 49
Ghiandole Surrenali. Cap.13 49
Discoidin Domain Receptor 1: a new therapeutic target in cancers with activated IR-A/ IGF-II loop. 48
In breast cancer cells IGF-I induces upregulation of DDR1 by suppressing miR199a-5p via the PI3K/AKT pathway 48
PPAR-g Agonists and their Effects on IGF-I Receptor Signaling: Implications for Cancer 47
GPER1 is regulated by insulin in cancer cells and cancer associated fibroblasts 47
Evaluation of glycemic status and subclinical atherosclerosis in familial hypercholesterolemia subjects with or without LDL receptor mutation 46
Intracellular signaling elicited by insulin-like growth factor I upon binding to insulin receptor isoform A 46
In prostate cancer cells metformin inhibits the cross-talk between membrane-initiated androgens and IGF-IR 46
Proinsulin stimulates biological effects through the isoform A of insulin receptor 46
Clinical and Molecular Biomarkers for Diagnosis and Staging of NAFLD 45
The lauric acid-activated signaling prompts apoptosis in cancer cells 44
Overexpression of the IGF-I receptor and of insulin receptor isoform A in progenitor/stem cells from human thyroid cancer 44
Funzioni Endocrine di Cuore, Rene e Polmone 44
The RET Kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells 44
Pericytes as Key Players in Retinal Diseases: a Comprehensive narrative review. 43
Mitochondrial RNAs as Potential Biomarkers of Functional Impairment in Diabetic Kidney Disease 43
Insulin/IGF signaling and discoidin domain receptors: An emerging functional connection 43
Nonalcoholic Fatty Liver: a possible NewTarget for Type 2 Diabetes Prevention and Treatment 43
Trabectedin Efficacy in Ewing Sarcoma Is Greatly Increased by Combination with Anti-IGF Signaling Agents. 43
Ghiandole Surrenali. Cap.15 43
Circulating Coding and Long Non-Coding RNAs as Potential Biomarkers of Idiopathic Pulmonary Fibrosis 43
Insulin-Like Growth Factor-I Receptor biological functions require Discoidin Domain Receptor 1. 42
The role of Metformin in the managment of NAFDL 42
Proinsulin may exert biological effects in MCF-7 human cancer cells through both isoform A of the insulin receptor and atypical IGF-I Receptors 41
EDITORIAL ON THE RESEARCH TOPIC: “CLINICAL AND MOLECULAR EPIDEMIOLOGY OF THYROID CANCER OF FOLLICULAR ORIGIN” 41
Discoidin domain receptor 1 is a new mediator of insulin receptor in breast cancer cells 41
HMGA1 inibisce le funzioni delle proteine appartenenti alla famiglia di p53 in cellule di carcinoma tiroideo 41
Espressione e funzioni di p63 nel carcinoma tiroideo 40
Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation 40
The Role of Pericytes in Inner Ear Disorders: A Comprehensive Review 40
New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer 39
Gonadi. Cap. 16 39
Thyroid cancer development and progression: emerging role of cancer stem cells 38
Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines 38
The insulin receptor and cancer 38
Gonadi. Cap.14 37
Metformin inhibits the androgens mediated up-regulation of Insulin Growth Factor-I Receptor in prostate cancer cells 37
In PCOS patients the addition of low-dose spironolactone induces a more marked reduction of clinical and biochemical hyperandrogenism than metformin alone 37
Overexpression of the insulin receptor isoform A in breast cancer cells has complex effect on glucose metabolism. 36
Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway 36
Neoplasie della tiroide 35
Novel aspects concerning the functional cross-talk between the insulin/IGF-I system and estrogen signaling in cancer cells 34
Metformin inhibits androgen-induced IGF-IR upregulation in prostate cancer cells by disrupting membrane initiated androgen signaling 34
Vie di segnalazione attivate dall’IGF-I dopo legame con l’isoforma A del recettore insulinico 34
mTOR is a therapeutic target in thyroid cancer: determinants of rapamycin response in human thyroid cancer cell lines 33
The insulin receptor: a new target for cancer therapy 33
Recent insights into the pathogenesis of autoimmune hypophysitis 33
Metformin: When Should We Fear Lactic Acidosis? 32
Totale 5.422
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Categoria #
all - tutte 55.260
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.260
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201 0 0 0 0 0 0 0 0 0 0 1 0
2020/2021986 204 23 98 102 17 96 1 128 45 131 25 116
2021/2022637 1 11 0 142 13 19 34 120 36 82 35 144
2022/20231.659 247 124 26 196 125 225 18 174 243 55 182 44
2023/20241.326 73 169 118 52 174 43 250 52 23 55 199 118
2024/20251.584 105 55 156 33 198 117 139 156 268 357 0 0
Totale 6.204