IRIS
MALAGUARNERA, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 2.671
EU - Europa 1.839
AS - Asia 474
AF - Africa 26
Continente sconosciuto - Info sul continente non disponibili 16
OC - Oceania 5
SA - Sud America 4
Totale 5.035
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Nazione #
US - Stati Uniti d'America 2.555
IE - Irlanda 424
GB - Regno Unito 327
UA - Ucraina 303
HK - Hong Kong 206
DE - Germania 192
IT - Italia 160
SG - Singapore 158
SE - Svezia 135
CH - Svizzera 118
CA - Canada 110
FI - Finlandia 91
IN - India 35
HR - Croazia 30
CN - Cina 28
EG - Egitto 21
CZ - Repubblica Ceca 17
EU - Europa 16
IR - Iran 16
TR - Turchia 13
RU - Federazione Russa 10
FR - Francia 9
BE - Belgio 6
PH - Filippine 6
TW - Taiwan 6
MX - Messico 5
AU - Australia 4
NL - Olanda 4
LT - Lituania 3
BR - Brasile 2
HU - Ungheria 2
IL - Israele 2
MA - Marocco 2
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
AT - Austria 1
BG - Bulgaria 1
CL - Cile 1
CR - Costa Rica 1
ES - Italia 1
GR - Grecia 1
IS - Islanda 1
JP - Giappone 1
LV - Lettonia 1
MC - Monaco 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PE - Perù 1
RO - Romania 1
SC - Seychelles 1
TJ - Tagikistan 1
ZA - Sudafrica 1
Totale 5.035
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Città #
Chandler 632
Dublin 410
London 305
Jacksonville 290
Boardman 286
Hong Kong 202
Santa Clara 132
Zurich 118
Wilmington 115
Princeton 110
Toronto 102
Singapore 101
Ashburn 91
Helsinki 91
Chicago 64
Bareggio 42
Catania 35
Redmond 32
Zagreb 30
Cairo 18
Brno 17
Milan 15
Munich 14
Kocaeli 12
Norwalk 10
Tappahannock 10
Cambridge 9
Falkenstein 9
Leawood 9
Palermo 9
Capo D'orlando 7
Carrara 6
Des Moines 6
Fairfield 6
Monmouth Junction 6
Taichung 6
Bremen 5
Brussels 5
Frankfurt am Main 5
Gustavo Adolfo Madero 5
Isfahan 5
New York 5
St Petersburg 5
Strasbourg 5
Andover 4
Bangalore 4
Bengaluru 4
Enna 4
New Delhi 4
Piscataway 4
Pune 4
Quezon City 4
Redwood City 4
San Mateo 4
Southend 4
Agrigento 3
Augusta 3
Edinburgh 3
Guangzhou 3
Ma On Shan 3
Menlo Park 3
Nanjing 3
Ottawa 3
Rome 3
Seattle 3
Trieste 3
Woodbridge 3
Zhengzhou 3
Aci Catena 2
Amsterdam 2
Ann Arbor 2
Ardabil 2
Bari 2
Brisbane 2
Centuripe 2
Clifton 2
Dallas 2
Damietta 2
Fishers 2
Kochi 2
Kunming 2
Laval 2
Mumbai 2
Pasay 2
Sabz 2
Sacramento 2
São Paulo 2
West Jordan 2
Agouza 1
Antwerp 1
Athens 1
Baltimore 1
Beijing 1
Berlin 1
Brooklyn 1
Cava de' Tirreni 1
Central 1
Chelyabinsk 1
Christchurch 1
Coventry 1
Totale 3.532
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Nome #
Orobanche crenata extracts exerts antitumor activity “in vitro” 143
c-ABL tyrosine kinase inhibits insulin induced proliferation and migration in HepG2 cancer cells: role of focal adhesion kinase 115
p73 tumor suppressor activity is impaired in thyroid cancer 103
p53 family proteins in thyroid cancer 99
TAp63 antagonizes p53 oncosuppressor function in thyroid cancer cells 94
The p53-homologue p63 may promote thyroid cancer progression 88
Immunopurification and quantitative proteomics reveal novel molecular mechanisms of signal diversification between the two insulin receptor isoforms. 87
TAp73? Increases p53 tumor suppressor activity in thyroid cancer cells via inhibition of Mdm2-mediated degradation 81
TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation 80
The IGF2/IRA loop affects the metabolic flexibility of breast cancer cells 68
The Emerging Role of Insulin Receptor Isoforms in Thyroid Cancer: Clinical Implications and New Perspectives 66
Targeting Discoidin Domain Receptor 1 as a novel strategy to downregulate Insulin/IGF axis in cancer cells. 66
Discoidin Domain Receptor 1 (DDR1) modulates the expression of insulin receptor and its differential splicing both in thyroid and breast cancer cells 66
Orobanche crenata Forssk. Extract Affects Human Breast Cancer Cell MCF-7 Survival and Viral Replication 66
DDR1 è un nuovo regolatore dell’espressione e della funzione del recettore insulinico 64
In poorly differentiated thyroid cancer cells autocrine IR-A/IGF2 signaling activates a feed-forward loop involving DDR1 and its newly identified non-canonical actions. 64
The Insulin/IGF signaling affects the metabolic flexibility of breast cancer cells 64
Carcinoma anaplastico della tiroide: p53 e p73 hanno un effetto sinergico nell'indurre apoptosi 61
The insulin receptor isoform A plays a role in thyrospheres growth and differentiation 59
NORMAL AND CANCER THYROID PROGENITOR CELLS: ROLE OF INSULIN RECEPTOR ISOFORMS AND INSULIN-LIKE GROWTH FACTOR RECEPTOR IN GROWTH AND DIFFERENTIATION 57
Discoidin Domain Receptor 1 (DDR1) interacts with IGFI-R and modulates its oncogenic role 57
Chronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (a-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cells. 55
Discoidin Domain Receptor 1 crosstalk with isoform A of Insulin Receptor affects stem-like phenotype in cancer cells. 54
Proinsulin is a ligand of isoform A of the insulin receptor 52
PPAR-γ Agonists As Antineoplastic Agents in Cancers with Dysregulated IGF Axis 51
Role of c-ABL in directing metabolic versus mitogenic effects in insulin receptor signaling 51
Comparative proteomic analysis of insulin receptor isoform A and B signaling 49
IGF-I and Insulin Receptor families in Cancer 49
Thyroid Cancer and Circadian Clock Disruption 49
Direct Effects of D-Chiro-Inositol on Insulin Signaling and Glucagon Secretion of Pancreatic Alpha Cells 49
Candidate genes of SARS-CoV-2 gender susceptibility 49
Involvement of c-ABL tyrosine kinase in insulin and IGF-I signaling 48
Both the insulin receptor isoform A and the IGF-I receptor mediate the effects of IGF-II in human thyroid stem cells 48
Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD 48
Ruolo di p73 nella progressione tumorale tiroidea 47
The insulin and igf-I pathway in endocrine glands carcinogenesis 47
A novel functional cross-talk between the IGF-I receptor and Discoidin Domain Receptor 1 in breast cancer cells. 47
Co-targeting IR/IGF-1R and DDR1 exerts additive effects in reducing stem-like features in thyrospheres from poorly differentiated thyroid cancer cell lines 47
A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer 46
Discoidin Domain Receptor 1 modulates Insulin Receptor isoform A expression and biological functions in breast cancer 46
The combined pharmacological inhibition of Discoidin Domanin Receptor 1 and Insulin Receptor exert antitumor effects in poorly differentiated thyroid cancer cells 46
mTOR signling is required for DNA synthesis induced by either RET/PTC, oncogenic RAS or BRAF in rat thyroid PCCL3 cells 46
Cooperation of p73 and p53 in anaplastic thyroid cancer cell apoptosis 45
Overlaps between the Insulin and IGF-I receptor in cancer 45
GPER1 is regulated by insulin in cancer cells and cancer associated fibroblasts 44
Discoidin Domain Receptor 1 affects Insulin Receptor expression and biological actions in breast cancer cells. 43
Discoidin Domain Receptor 1: a new therapeutic target in cancers with activated IR-A/ IGF-II loop. 43
DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop. 43
BRAFV600E mutation is associated with preferential sensitivity to MEK inhibition in thyroid cancer cell lines 43
In prostate cancer cells metformin inhibits the cross-talk between membrane-initiated androgens and IGF-IR 43
HMGA1 inhibits the function of p53 family members in thyroid cancer cells 43
The crosstalk between the insulin receptor isoform A and Discoidin Domain Receptor 1 regulates breast cancer cell biology and stemness. 42
Modeling BRAF-induced thyroid tumorigenesis in mice:evidence for a causal role of oncogenic BRAF activation on loss of thyroid differentiated function in vivo 42
Ghiandole Surrenali. Cap.13 42
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice 42
Clinical and Molecular Biomarkers for Diagnosis and Staging of NAFLD 41
Overexpression of the IGF-I receptor and of insulin receptor isoform A in progenitor/stem cells from human thyroid cancer 40
In breast cancer cells IGF-I induces upregulation of DDR1 by suppressing miR199a-5p via the PI3K/AKT pathway 40
Recent advances on the stimulatory effects of metals in breast cancer 40
Funzioni Endocrine di Cuore, Rene e Polmone 40
Proinsulin stimulates biological effects through the isoform A of insulin receptor 40
Insulin/IGF signaling and discoidin domain receptors: An emerging functional connection 39
PPAR-g Agonists and their Effects on IGF-I Receptor Signaling: Implications for Cancer 39
Ghiandole Surrenali. Cap.15 39
Mitochondrial RNAs as Potential Biomarkers of Functional Impairment in Diabetic Kidney Disease 38
Insulin-Like Growth Factor-I Receptor biological functions require Discoidin Domain Receptor 1. 38
Intracellular signaling elicited by insulin-like growth factor I upon binding to insulin receptor isoform A 38
Nonalcoholic Fatty Liver: a possible NewTarget for Type 2 Diabetes Prevention and Treatment 38
HMGA1 inibisce le funzioni delle proteine appartenenti alla famiglia di p53 in cellule di carcinoma tiroideo 38
The RET Kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells 38
The role of Metformin in the managment of NAFDL 38
Circulating Coding and Long Non-Coding RNAs as Potential Biomarkers of Idiopathic Pulmonary Fibrosis 38
The lauric acid-activated signaling prompts apoptosis in cancer cells 37
Trabectedin Efficacy in Ewing Sarcoma Is Greatly Increased by Combination with Anti-IGF Signaling Agents. 37
Espressione e funzioni di p63 nel carcinoma tiroideo 37
EDITORIAL ON THE RESEARCH TOPIC: “CLINICAL AND MOLECULAR EPIDEMIOLOGY OF THYROID CANCER OF FOLLICULAR ORIGIN” 37
Discoidin domain receptor 1 is a new mediator of insulin receptor in breast cancer cells 37
Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation 36
The insulin receptor and cancer 35
Thyroid cancer development and progression: emerging role of cancer stem cells 34
Proinsulin may exert biological effects in MCF-7 human cancer cells through both isoform A of the insulin receptor and atypical IGF-I Receptors 34
Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines 34
Metformin inhibits the androgens mediated up-regulation of Insulin Growth Factor-I Receptor in prostate cancer cells 34
In PCOS patients the addition of low-dose spironolactone induces a more marked reduction of clinical and biochemical hyperandrogenism than metformin alone 34
Gonadi. Cap. 16 34
New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer 33
Overexpression of the insulin receptor isoform A in breast cancer cells has complex effect on glucose metabolism. 32
Metformin inhibits androgen-induced IGF-IR upregulation in prostate cancer cells by disrupting membrane initiated androgen signaling 31
The insulin receptor: a new target for cancer therapy 31
Neoplasie della tiroide 31
Proinsulin mediates proliferative effects by activating the isoform A of the insulin receptor 30
Novel aspects concerning the functional cross-talk between the insulin/IGF-I system and estrogen signaling in cancer cells 29
Vie di segnalazione attivate dall’IGF-I dopo legame con l’isoforma A del recettore insulinico 29
The emerging role of Insulin and Insulin-like growth factor signaling in Cancer Stem Cells 29
Recent insights into the pathogenesis of autoimmune hypophysitis 29
Metformin: When Should We Fear Lactic Acidosis? 28
Gonadi. Cap.14 28
Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway 28
mTOR is a therapeutic target in thyroid cancer: determinants of rapamycin response in human thyroid cancer cell lines 27
IGF-I receptor expression, trafficking, and downstream signaling is regulated by Discoidin Domain Receptor 1. 27
Totale 4.796
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Categoria #
all - tutte 47.755
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.755
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20208 0 0 0 0 0 2 2 3 0 0 1 0
2020/2021986 204 23 98 102 17 96 1 128 45 131 25 116
2021/2022637 1 11 0 142 13 19 34 120 36 82 35 144
2022/20231.659 247 124 26 196 125 225 18 174 243 55 182 44
2023/20241.326 73 169 118 52 174 43 250 52 23 55 199 118
2024/2025628 107 55 157 33 200 76 0 0 0 0 0 0
Totale 5.248