IRIS
MALAGUARNERA, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 3.064
EU - Europa 2.008
AS - Asia 965
SA - Sud America 244
AF - Africa 45
Continente sconosciuto - Info sul continente non disponibili 16
OC - Oceania 5
Totale 6.347
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Nazione #
US - Stati Uniti d'America 2.927
IE - Irlanda 452
HK - Hong Kong 407
SG - Singapore 390
GB - Regno Unito 340
UA - Ucraina 305
DE - Germania 236
BR - Brasile 224
IT - Italia 188
SE - Svezia 136
CH - Svizzera 118
CA - Canada 117
FI - Finlandia 96
IN - India 38
FR - Francia 35
TR - Turchia 31
HR - Croazia 30
CN - Cina 28
EG - Egitto 24
CZ - Repubblica Ceca 17
IR - Iran 17
EU - Europa 16
RU - Federazione Russa 14
MX - Messico 13
NL - Olanda 8
AR - Argentina 7
PH - Filippine 7
BD - Bangladesh 6
BE - Belgio 6
TW - Taiwan 6
ZA - Sudafrica 6
AT - Austria 5
PK - Pakistan 5
AU - Australia 4
IL - Israele 4
IQ - Iraq 4
JM - Giamaica 4
KE - Kenya 4
LT - Lituania 4
MA - Marocco 4
PL - Polonia 4
SA - Arabia Saudita 4
AE - Emirati Arabi Uniti 3
EC - Ecuador 3
ES - Italia 3
KG - Kirghizistan 3
PE - Perù 3
TN - Tunisia 3
CL - Cile 2
CR - Costa Rica 2
HU - Ungheria 2
JP - Giappone 2
KR - Corea 2
LV - Lettonia 2
NP - Nepal 2
RO - Romania 2
VE - Venezuela 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BG - Bulgaria 1
CI - Costa d'Avorio 1
CO - Colombia 1
GR - Grecia 1
IS - Islanda 1
MC - Monaco 1
ML - Mali 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PA - Panama 1
PS - Palestinian Territory 1
PT - Portogallo 1
PY - Paraguay 1
SC - Seychelles 1
TJ - Tagikistan 1
UY - Uruguay 1
UZ - Uzbekistan 1
VN - Vietnam 1
Totale 6.347
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Città #
Chandler 632
Dublin 438
Hong Kong 403
London 305
Jacksonville 290
Boardman 285
The Dalles 162
Santa Clara 139
Singapore 130
Zurich 118
Wilmington 115
Princeton 110
Toronto 102
Ashburn 97
Helsinki 92
Chicago 66
Bareggio 42
Catania 39
Redmond 32
Zagreb 30
Munich 23
Cairo 18
Frankfurt am Main 18
São Paulo 18
Brno 17
Milan 16
Los Angeles 14
Istanbul 12
Kocaeli 12
Palermo 11
New York 10
Norwalk 10
Tappahannock 10
Cambridge 9
Falkenstein 9
Leawood 9
Brooklyn 7
Capo D'orlando 7
Carrara 7
Council Bluffs 7
Belo Horizonte 6
Dallas 6
Des Moines 6
Düsseldorf 6
Fairfield 6
Monmouth Junction 6
Rio de Janeiro 6
Taichung 6
Bremen 5
Brussels 5
Gustavo Adolfo Madero 5
Isfahan 5
Ribeirão Preto 5
Rome 5
St Petersburg 5
Strasbourg 5
Andover 4
Atlanta 4
Augusta 4
Bangalore 4
Bengaluru 4
Bexley 4
Boston 4
Brasília 4
Enna 4
Kingston 4
Londrina 4
Manaus 4
Mascalucia 4
Nairobi 4
New Delhi 4
Piscataway 4
Pune 4
Quezon City 4
Redwood City 4
San Francisco 4
San Mateo 4
Seattle 4
Sorocaba 4
Southend 4
São Bernardo do Campo 4
Turku 4
Warsaw 4
Agrigento 3
Amsterdam 3
Ankara 3
Anápolis 3
Aracaju 3
Bari 3
Bishkek 3
Campinas 3
Curitiba 3
Dhaka 3
Diadema 3
Edinburgh 3
Feira de Santana 3
Fortaleza 3
Gevelsberg 3
Goiânia 3
Guangzhou 3
Totale 4.118
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Nome #
Orobanche crenata extracts exerts antitumor activity “in vitro” 151
c-ABL tyrosine kinase inhibits insulin induced proliferation and migration in HepG2 cancer cells: role of focal adhesion kinase 129
p73 tumor suppressor activity is impaired in thyroid cancer 116
p53 family proteins in thyroid cancer 107
TAp63 antagonizes p53 oncosuppressor function in thyroid cancer cells 103
The p53-homologue p63 may promote thyroid cancer progression 99
Immunopurification and quantitative proteomics reveal novel molecular mechanisms of signal diversification between the two insulin receptor isoforms. 96
TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation 94
TAp73? Increases p53 tumor suppressor activity in thyroid cancer cells via inhibition of Mdm2-mediated degradation 90
Orobanche crenata Forssk. Extract Affects Human Breast Cancer Cell MCF-7 Survival and Viral Replication 79
The Emerging Role of Insulin Receptor Isoforms in Thyroid Cancer: Clinical Implications and New Perspectives 78
The IGF2/IRA loop affects the metabolic flexibility of breast cancer cells 77
Targeting Discoidin Domain Receptor 1 as a novel strategy to downregulate Insulin/IGF axis in cancer cells. 75
Carcinoma anaplastico della tiroide: p53 e p73 hanno un effetto sinergico nell'indurre apoptosi 74
Discoidin Domain Receptor 1 (DDR1) modulates the expression of insulin receptor and its differential splicing both in thyroid and breast cancer cells 73
In poorly differentiated thyroid cancer cells autocrine IR-A/IGF2 signaling activates a feed-forward loop involving DDR1 and its newly identified non-canonical actions. 72
The Insulin/IGF signaling affects the metabolic flexibility of breast cancer cells 72
DDR1 è un nuovo regolatore dell’espressione e della funzione del recettore insulinico 67
Chronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (a-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cells. 65
NORMAL AND CANCER THYROID PROGENITOR CELLS: ROLE OF INSULIN RECEPTOR ISOFORMS AND INSULIN-LIKE GROWTH FACTOR RECEPTOR IN GROWTH AND DIFFERENTIATION 64
The insulin receptor isoform A plays a role in thyrospheres growth and differentiation 64
Co-targeting IR/IGF-1R and DDR1 exerts additive effects in reducing stem-like features in thyrospheres from poorly differentiated thyroid cancer cell lines 64
Comparative proteomic analysis of insulin receptor isoform A and B signaling 63
PPAR-γ Agonists As Antineoplastic Agents in Cancers with Dysregulated IGF Axis 63
Discoidin Domain Receptor 1 crosstalk with isoform A of Insulin Receptor affects stem-like phenotype in cancer cells. 63
Proinsulin is a ligand of isoform A of the insulin receptor 62
Discoidin Domain Receptor 1 (DDR1) interacts with IGFI-R and modulates its oncogenic role 62
Role of c-ABL in directing metabolic versus mitogenic effects in insulin receptor signaling 59
Both the insulin receptor isoform A and the IGF-I receptor mediate the effects of IGF-II in human thyroid stem cells 59
Thyroid Cancer and Circadian Clock Disruption 59
Candidate genes of SARS-CoV-2 gender susceptibility 59
Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD 59
A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer 58
Discoidin Domain Receptor 1 affects Insulin Receptor expression and biological actions in breast cancer cells. 57
Direct Effects of D-Chiro-Inositol on Insulin Signaling and Glucagon Secretion of Pancreatic Alpha Cells 57
Involvement of c-ABL tyrosine kinase in insulin and IGF-I signaling 56
DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop. 56
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice 56
A novel functional cross-talk between the IGF-I receptor and Discoidin Domain Receptor 1 in breast cancer cells. 56
Evaluation of glycemic status and subclinical atherosclerosis in familial hypercholesterolemia subjects with or without LDL receptor mutation 55
Cooperation of p73 and p53 in anaplastic thyroid cancer cell apoptosis 55
IGF-I and Insulin Receptor families in Cancer 55
The insulin and igf-I pathway in endocrine glands carcinogenesis 55
BRAFV600E mutation is associated with preferential sensitivity to MEK inhibition in thyroid cancer cell lines 55
The crosstalk between the insulin receptor isoform A and Discoidin Domain Receptor 1 regulates breast cancer cell biology and stemness. 54
The combined pharmacological inhibition of Discoidin Domanin Receptor 1 and Insulin Receptor exert antitumor effects in poorly differentiated thyroid cancer cells 54
Recent advances on the stimulatory effects of metals in breast cancer 53
Ruolo di p73 nella progressione tumorale tiroidea 53
Overlaps between the Insulin and IGF-I receptor in cancer 53
HMGA1 inhibits the function of p53 family members in thyroid cancer cells 53
Modeling BRAF-induced thyroid tumorigenesis in mice:evidence for a causal role of oncogenic BRAF activation on loss of thyroid differentiated function in vivo 52
Discoidin Domain Receptor 1 modulates Insulin Receptor isoform A expression and biological functions in breast cancer 51
Ghiandole Surrenali. Cap.13 51
In prostate cancer cells metformin inhibits the cross-talk between membrane-initiated androgens and IGF-IR 51
mTOR signling is required for DNA synthesis induced by either RET/PTC, oncogenic RAS or BRAF in rat thyroid PCCL3 cells 51
Discoidin Domain Receptor 1: a new therapeutic target in cancers with activated IR-A/ IGF-II loop. 50
In breast cancer cells IGF-I induces upregulation of DDR1 by suppressing miR199a-5p via the PI3K/AKT pathway 50
PPAR-g Agonists and their Effects on IGF-I Receptor Signaling: Implications for Cancer 49
GPER1 is regulated by insulin in cancer cells and cancer associated fibroblasts 49
Proinsulin stimulates biological effects through the isoform A of insulin receptor 49
Clinical and Molecular Biomarkers for Diagnosis and Staging of NAFLD 49
Overexpression of the IGF-I receptor and of insulin receptor isoform A in progenitor/stem cells from human thyroid cancer 48
Circulating Coding and Long Non-Coding RNAs as Potential Biomarkers of Idiopathic Pulmonary Fibrosis 48
Intracellular signaling elicited by insulin-like growth factor I upon binding to insulin receptor isoform A 47
Pericytes as Key Players in Retinal Diseases: a Comprehensive narrative review. 46
Mitochondrial RNAs as Potential Biomarkers of Functional Impairment in Diabetic Kidney Disease 46
Insulin/IGF signaling and discoidin domain receptors: An emerging functional connection 46
The lauric acid-activated signaling prompts apoptosis in cancer cells 46
Nonalcoholic Fatty Liver: a possible NewTarget for Type 2 Diabetes Prevention and Treatment 46
The RET Kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells 46
Trabectedin Efficacy in Ewing Sarcoma Is Greatly Increased by Combination with Anti-IGF Signaling Agents. 45
Funzioni Endocrine di Cuore, Rene e Polmone 45
The role of Metformin in the managment of NAFDL 45
Insulin-Like Growth Factor-I Receptor biological functions require Discoidin Domain Receptor 1. 44
Discoidin domain receptor 1 is a new mediator of insulin receptor in breast cancer cells 44
Ghiandole Surrenali. Cap.15 44
HMGA1 inibisce le funzioni delle proteine appartenenti alla famiglia di p53 in cellule di carcinoma tiroideo 43
The Role of Pericytes in Inner Ear Disorders: A Comprehensive Review 43
Proinsulin may exert biological effects in MCF-7 human cancer cells through both isoform A of the insulin receptor and atypical IGF-I Receptors 42
EDITORIAL ON THE RESEARCH TOPIC: “CLINICAL AND MOLECULAR EPIDEMIOLOGY OF THYROID CANCER OF FOLLICULAR ORIGIN” 42
Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation 42
Novel aspects concerning the functional cross-talk between the insulin/IGF-I system and estrogen signaling in cancer cells 41
New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer 41
Espressione e funzioni di p63 nel carcinoma tiroideo 41
Gonadi. Cap. 16 41
The insulin receptor and cancer 40
Thyroid cancer development and progression: emerging role of cancer stem cells 39
Gonadi. Cap.14 39
Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines 39
Neoplasie della tiroide 39
Overexpression of the insulin receptor isoform A in breast cancer cells has complex effect on glucose metabolism. 38
Metformin inhibits the androgens mediated up-regulation of Insulin Growth Factor-I Receptor in prostate cancer cells 38
In PCOS patients the addition of low-dose spironolactone induces a more marked reduction of clinical and biochemical hyperandrogenism than metformin alone 38
Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway 37
Diet and Nutrients in Rare Neurological Disorders: Biological, Biochemical, and Pathophysiological Evidence 36
Metformin inhibits androgen-induced IGF-IR upregulation in prostate cancer cells by disrupting membrane initiated androgen signaling 36
Vie di segnalazione attivate dall’IGF-I dopo legame con l’isoforma A del recettore insulinico 36
Proinsulin mediates proliferative effects by activating the isoform A of the insulin receptor 35
mTOR is a therapeutic target in thyroid cancer: determinants of rapamycin response in human thyroid cancer cell lines 35
Recent insights into the pathogenesis of autoimmune hypophysitis 35
Totale 5.682
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Categoria #
all - tutte 58.555
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.555
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021986 204 23 98 102 17 96 1 128 45 131 25 116
2021/2022637 1 11 0 142 13 19 34 120 36 82 35 144
2022/20231.659 247 124 26 196 125 225 18 174 243 55 182 44
2023/20241.326 73 169 118 52 174 43 250 52 23 55 199 118
2024/20251.954 105 55 156 33 198 117 139 156 268 364 253 110
Totale 6.574